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Study of pathophysiology of peptic ulcer in the aged with special reference to gastric acid pepsin secretion



Study of pathophysiology of peptic ulcer in the aged with special reference to gastric acid pepsin secretion



Gastroenterological Endoscopy 27(9): 1723-1730



Radioimmunoassay of serum pepsinogen I (PG I) and serum pepsinogen II (PG II) was performed to 209 normal controls, 112 gastric ulcer cases and 142 duodenal ulcer cases of which diagnosis were made endoscopically. One hundred and six cases of peptic ulcer received the gastric analyses and the endoscopic Congo red test on the other day, and then the age differences of those in peptic ulcer cases were analysed. Results were obtained as follows: (1) There were more cases of gastric ulcer located in high position found in the aged, which showed low levels of serum pepsinogen and low gastric acid-pepsin outputs, but gastric ulcer cases of the aged located in low position showed high levels of serum pepsinogen and high gastric acid-pepsin outputs, those were not different from the other younger ages. (2) Almost all the cases of duodenal ulcer in the aged had a closed-type of glandular border by Congo red test, which showed high levels of serum pepsinogen and high gastric acid-pepsin outputs as well as the other younger ages. In conclusion, there was no special secretion function which was shown in peptic ulcer cases of the aged from the view points of the stage and location of peptic ulcer.

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赢8娱乐糖果配对游戏