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1- -Acetylmethadol (Laam) Pharmacokinetics and Metabolism: Current Status



1- -Acetylmethadol (Laam) Pharmacokinetics and Metabolism: Current Status



The American Journal of Drug and Alcohol Abuse 2(3-4): 301-305




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Accession: 068447975

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DOI: 10.3109/00952997509005655


Related references

1-alpha-acetylmethadol(LAAM) pharmacokinetics and metabolism: current status. American Journal of Drug and Alcohol Abuse 2(3-4): 301-305, 1975

Pharmacodynamic profiles of 1-alpha-acetylmethadol (LAAM) and its N-demethylated metabolites, nor-LAAM and dinor-LAAM, during self-administration in the dependent rat. Journal of Pharmacology and Experimental Therapeutics 210(3): 453-457, 1979

Uptake of l-alpha-acetylmethadol (LAAM) and its analgesically active metabolites, nor-LAAM and dinor-LAAM, in the isolated perfused rat lung. Drug Metabolism and Disposition: the Biological Fate of Chemicals 11(5): 411-416, 1983

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Pharmacokinetics and metabolism of l-alpha-[O,O'-3H2]-acetyl normethadol (nor-LAAM), the active metabolite of LAAM, in acutely and chronically treated rhesus monkeys. Journal of Pharmacology and Experimental Therapeutics 214(3): 599-607, 1980

Role of CYP3A in the metabolism, disposition and clinical effects of 1-a-acetylmethadol (LAAM) in humans. Clinical Pharmacology and Therapeutics 73(2): P62-P62, 2003

The effect of ethanol on the metabolism of chronically-administered l-alpha-acetylmethadol (LAAM) in the rhesus monkey. Research Communications in Chemical Pathology and Pharmacology 21(2): 351-354, 1978

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Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): potential contribution of intestinal metabolism to presystemic clearance and bioactivation. Journal of Pharmacology and Experimental Therapeutics 298(3): 1021-1032, 2001

Metabolism of levo-alpha-Acetylmethadol (LAAM) by human liver cytochrome P450: involvement of CYP3A4 characterized by atypical kinetics with two binding sites. Journal of Pharmacology and Experimental Therapeutics 297(1): 410-422, 2001

Laam ( l - -Acetylmethadol) Study in St. Louis. The American Journal of Drug and Alcohol Abuse 2(3-4): 341-352, 1975

Stereospecific radioimmunoassay of alpha-l-acetylmethadol (LAAM). Journal of Pharmacology and Experimental Therapeutics 215(1): 205-212, 1980

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Cardiac effects of 1-α-acetylmethadol (LAAM) in different species. General Pharmacology: Vascular System 10(5): 359-362, 1979

L-Alpha-acetylmethadol (LAAM): prognostic considerations. American Journal of Psychiatry 133(7): 814-819, 1976





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